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KMID : 0355819930170010087
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Korean Journal of Oral Anatomy
1993 Volume.17 No. 1 p.87 ~ p.98
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Immunohistochemical Localization of Type I and Type II Collagen in Developing Rat Dental Tissues
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Abstract
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Collagen is the most abundant vertebrate protein wit at least twelve different types of mulecule. Type I and type III collagen are the most important collagen in dental tissues. In order to localize type I and type III collagen in developing
dental
tissues, immunohistochemical study was performed. The materials used were the molar toot germs of about 14-day-old Sprague Dawley rats.
@ES The results were as follows.
@EN 1. For both of the type I and type III collagen, periodontal ligament and dental follicle show strong immunoreactivity, submucosal lamina propria and pulp are moderate but enamel, dental organ and oral epithelium are negative.
2. Type I collagen is localized in alveolar bone and dentin. Predentin showes stronger immunoreactivity than dentin.
3. Periodontal ligament shows stronger immunoreactivity for type II collagen than for type I collagen. Sharpey's fiber imbedded into alveolar bone shows predominantly strong immunoreactivity.
4. just beneath the odontoblast layer and lamina adjacent to oral epithelium show stronger immunoreactivity for type III collagen.
5. Matrices of early acellular cementum shows strong immunoreactivity for the I collagen but not for type III collagen.
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KEYWORD
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